International Organization of Zerophiliacs Announces FDA Filing for
Z-Chromosome Assay

LOS ANGELES, CA., July 18, 2007 The International Organization of Zerophiliacs LLC (IOZ) today announced initial filings with the FDA for its Z-chromosome assay. 

IOZ's test is a Mass Spectrometry assay to detect the presence of the Z-Chromosome in human DNA.   As the first assay using metabolites as an indicator, IOZ's test would represent a major breakthrough in providing the first widely accepted indicator of a rare genetic condition at a fraction of the cost of direct DNA analysis.

"We believe that an accurate, affordable assay for the presence of the Z-Chromosome will enable medical professionals to obtain accurate statistical data on the prevalence of Zerophilia among the general population, and serve as a critical first step to advancing research on this little-known and widely misunderstood condition," said Czierny Ptolemy, Vice President Laboratory Operations of IOZ. "We are pleased to be in a position to submit our assay for clearance by the FDA after less than three years in development.† †FDA clearance would encourage acceptance of our assay as a standard clinical test among physicians, and thereby increase the public's awareness of Zerophilia, and help it to more quickly gain acceptance among the scientific research community and policymakers, as a normal, non-threatening genetic condition.† We believe that the presence of a latent Z-Chromosome, especially among young people aged 15-25, is vastly underreported."

The prevalence of a latent Z-Chromomsome among the general U.S. population is unknown, but there is growing evidence that it is far more common than researchers initially believed.  Speaking on condition of anonymity, a prominent molecular biology researcher at Yale University reports that "Closed-door research at various American universities suggest that the latent Z-Chromosome may be present in as many as ten to twelve percent of college students.  We have tremendous respect for research conducted by the International Organization of Zerophiliacs as well as that by the Gruppo Italiano per lo Studio della Neuromorfologia (G.I.S.N.) of Urbino, Italy . In just a few years, a short time frame for this type of research, they have accomplished important work in the study of Neuromorphology and are certain to play a key role in advancing our understanding of this condition."

The International Organization of Zerophiliacs formed in May, 2003 with funding from private doctors and research scientists, "to combat irrational fears and misinformation regarding Zerophilia and to provide a safe, anonymous community for Zerophiliacs and those with a Z-Chromosome."  It quickly established itself as the leading source for information regarding Zerophilia worldwide.  In June of 2004, under the supervision of renowned neuro-morphologist, Czierny Ptolemy, the IOZ opened its Laboratory Services Online offering free Z-Chromosome testing to the general public.   

Cautionary Statement for purposes of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995: From time to time, information provided by the International Organization of Zerophiliacs may contain forward-looking information that involves risks and uncertainties. In particular, statements contained in this release that are not historical facts (including but not limited to statements concerning anticipated filings with the FDA) may be "forward looking" statements. Actual results may differ from those stated in any forward-looking statements. Factors that may cause such differences include but are not limited to risks associated with new services offered, associations with European entities not officially affiliated with the Company, government regulation, including but not limited to FDA regulations, competition and general economic conditions. SOURCE International Organization of Zerophiliacs.

Contact: Info@Zerophilia.net. Laboratory Services Website: www.Zerophilia.net